董永辉,教授，硕士生导师
一、联系方式：
福建农林大学海峡联合研究院福州35000215
Email: yonghui.dong@gmail.com
二、教育背景：
20010.10-2014.06意大利特伦托大学，博士
2008.09-2010.09意大利博洛尼亚大学, 意大利; 德国慕尼黑工业大学; 奥地利维也纳自然资源与生命科学大学 , 硕士
2003.09-2006.07西北农林科技大学，学士
三、工作经历：
2024.05-至今福建农林大学海峡联合研究院，教授
2022.06-2024.04以色列魏茨曼科学研究所，研究员
2021.01-2022.05 以色列特拉维夫大学，研究员
2014.12-2021.12 以色列魏茨曼科学研究所，博士后
2014.07-2014.11 意大利特伦托大学，研究助理
四、研究兴趣：
我的研究兴趣集中在将空间代谢组学、经典代谢组学和生物信息学相结合，以揭示植物代谢途径中的核心节点和调控机制，从而深入理解植物是如何灵活地调整其代谢网络，以适应不断变化的环境条件。
(1) 开发针对植物空间代谢组学的先进分析方法
(2) 开发针对质谱成像（MSI）和代谢组学数据分析的先进算法和高效软件工具
(3) 化学生态学
五、论文(#共第一作者, *共通讯作者)：
2023
Wang, Y., Dong, Y#., Duan, X., Luan, Y., Li, Q., Pang, Y., Sun, F. and Gou, M., (2023). A complete prostaglandin pathway from synthesis to inactivation in the oral gland of the jawless vertebrate lamprey, Lethenteron camtschaticum. Developmental & Comparative Immunology, 148, p.104903.
Gou, M., Duan, X., Li, J., Wang, Y., Li, Q., Pang, Y. and Dong, Y*., (2023). Spatial Metabolomics Reveals the Multifaceted Nature of Lamprey Buccal Gland and Its Diverse Mechanisms for Blood-Feeding. Communications Biology, 6(1), p.881.
Berman, P., de Haro, L.A., Jozwiak, A., Panda, S., Pinkas, Z., Dong, Y., Cveticanin, J., Barbole, R., Livne, R., Scherf, T. and Shimoni, E., (2023). Parallel evolution of cannabinoid biosynthesis. Nature plants, 9(5), pp.817-831.
Dong, Y., Shachaf, N., Feldberg, L., Rogachev, I., Heinig, U. and Aharoni, A., (2023). PICA: Pixel Intensity Correlation Analysis for Deconvolution and Metabolite Identification in Mass Spectrometry Imaging. Analytical Chemistry, 95(2), pp.1652-1662.
2022
Morgan, L., Birkler, R.I.D., Shaham-Niv, S., Dong, Y., Wachsman, T., Carmi, L., Yakobson, B., Adler-Abramovich, L., Cohen, H., Zohar, J. and Bateson, M., (2022). Saliva metabolome alterations after acute stress. Scientific Reports, 12(1), p.18470.
Luan, Y., Dong, Y#., Duan, X., Wang, X., Pang, Y., Li, Q. and Gou, M., 2022. TMT-based quantitative proteomics reveals protein biomarkers from cultured Pacific abalone (Haliotis discus hannai) in different regions. Food Chemistry: X, 14, p.100355.
Dong, Y., Kazachkova, Y., Gou, M., Morgan, L., Wachsman, T., Gazit, E. and Birkler, R.I.D., (2022). RawHummus: an R Shiny app for automated raw data quality control in metabolomics. Bioinformatics, 38(7), pp.2072-2074.
Dondini, L., Domenichini, C., Dong, Y., Gennari, F., Bassi, D., Foschi, S., Lama, M., Adami, M., De Franceschi, P., Cervellati, C. and Bergonzoni, L., (2022). Quantitative trait loci mapping and identification of candidate genes linked to fruit acidity in apricot (Prunus armeniaca L.). Frontiers in Plant Science, 13, p.838370.
Dong, Y. and Aharoni, A., (2022). Image to insight: exploring natural products through mass spectrometry imaging. Natural product reports, 39(7), pp.1510-1530.
Arya, G.C., Dong, Y#., Heinig, U., Shahaf, N., Kazachkova, Y., Aviv-Sharon, E., Nomberg, G., Marinov, O., Manasherova, E., Aharoni, A. and Cohen, H., (2022). The metabolic and proteomic repertoires of periderm tissue in skin of the reticulated Sikkim cucumber fruit. Horticulture research, 9, p.uhac092.
2021
Dong, Y., Feldberg, L., Rogachev, I. and Aharoni, A., (2021). Characterization of the PRODUCTION of ANTHOCYANIN PIGMENT 1 Arabidopsis dominant mutant using DLEMMA dual isotope labeling approach. Phytochemistry, 186, p.112740.
Kazachkova, Y., Zemach, I., Panda, S., Bocobza, S., Vainer, A., Rogachev, I., Dong, Y., Ben-Dor, S., Veres, D., Kanstrup, C. and Lambertz, S.K., (2021). The GORKY glycoalkaloid transporter is indispensable for preventing tomato bitterness. Nature plants, 7(4), pp.468-480.
Dong, Y., Wachsman, T., Morgan, L., Gazit, E. and Birkler, R.I.D., (2021). CCWeights: an R package and web application for automated evaluation and selection of weighting factors for accurate quantification using linear calibration curve. Bioinformatics Advances, 1(1), p.vbab029.
2020
Dong, Y., Sonawane, P., Cohen, H., Polturak, G., Feldberg, L., Avivi, S.H., Rogachev, I. and Aharoni, A., (2020). High mass resolution, spatial metabolite mapping enhances the current plant gene and pathway discovery toolbox. New Phytologist, 228(6), pp.1986-2002.
Korenblum, E., Dong, Y., Szymanski, J., Panda, S., Jozwiak, A., Massalha, H., Meir, S., Rogachev, I. and Aharoni, A., (2020). Rhizosphere microbiome mediates systemic root metabolite exudation by root-to-root signaling. Proceedings of the National Academy of Sciences, 117(7), pp.3874-3883.
2019
Dong, Y., Feldberg, L. and Aharoni, A., (2019). Miso: an R package for multiple isotope labeling assisted metabolomics data analysis. Bioinformatics, 35(18), pp.3524-3526.
Cohen, H., Dong, Y., Szymanski, J., Lashbrooke, J., Meir, S., Almekias-Siegl, E., Zeisler-Diehl, V.V., Schreiber, L. and Aharoni, A., (2019). A multilevel study of melon fruit reticulation provides insight into skin ligno-suberization hallmarks. Plant physiology, 179(4), pp.1486-1501.
Schleyer, G., Shahaf, N., Ziv, C., Dong, Y., Meoded, R.A., Helfrich, E.J., Schatz, D., Rosenwasser, S., Rogachev, I., Aharoni, A. and Piel, J., (2019). In plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids. Nature Microbiology, 4(3), pp.527-538.
2018
Feldberg, L., Dong, Y#., Heinig, U., Rogachev, I. and Aharoni, A., (2018). DLEMMA-MS-imaging for identification of spatially localized metabolites and metabolic network map reconstruction. Analytical chemistry, 90(17), pp.10231-10238.
Abraham, Y., Dong, Y., Aharoni, A. and Elbaum, R., (2018). Mapping of cell wall aromatic moieties and their effect on hygroscopic movement in the awns of stork’s bill. Cellulose, 25, pp.3827-3841.
2017
Dong, Y., Ferrazza, R., Anesi, A., Guella, G. and Franceschi, P., (2017). TLC surface integrity affects the detection of alkali adduct ions in TLC-MALDI analysis. Analytical and Bioanalytical Chemistry, 409, pp.5661-5666.
Polturak, G., Grossman, N., Vela-Corcia, D., Dong, Y., Nudel, A., Pliner, M., Levy, M., Rogachev, I. and Aharoni, A., (2017). Engineered gray mold resistance, antioxidant capacity, and pigmentation in betalain-producing crops and ornamentals. Proceedings of the National Academy of Sciences, 114(34), pp.9062-9067.
2016
Dong, Y., Li, B. and Aharoni, A., (2016). More than pictures: when MS imaging meets histology. Trends in Plant Science, 21(8), pp.686-698.
Dong, Y., Guella, G. and Franceschi, P., (2016). Impact of tissue surface properties on the desorption electrospray ionization imaging of organic acids in grapevine stem. Rapid Communications in Mass Spectrometry, 30(6), pp.711-718.
Dong, Y., Li, B., Malitsky, S., Rogachev, I., Aharoni, A., Kaftan, F., Svatoš, A. and Franceschi, P., (2016). Sample preparation for mass spectrometry imaging of plant tissues: a review. Frontiers in plant science, 7, p.60.
Qu, D., Yan, F., Meng, R., Jiang, X., Yang, H., Gao, Z., Dong, Y., Yang, Y. and Zhao, Z., (2016). Identification of microRNAs and their targets associated with fruit-bagging and subsequent sunlight re-exposure in the “Granny Smith” apple exocarp using high-throughput sequencing. Frontiers in plant science, 7, p.169880.
Li, B., Dunham, S.J., Dong, Y., Yoon, S., Zeng, M. and Sweedler, J.V., (2016). Analytical capabilities of mass spectrometry imaging and its potential applications in food science. Trends in food science & technology, 47, pp.50-63.
2015
Dong, Y., Guella, G., Mattivi, F. and Franceschi, P., (2015). High production of small organic dicarboxylate dianions by DESI and ESI. Journal of The American Society for Mass Spectrometry, 26(3), pp.386-389.
2012
Franceschi, P., Dong, Y., Strupat, K., Vrhovsek, U. and Mattivi, F., (2012). Combining intensity correlation analysis and MALDI imaging to study the distribution of flavonols and dihydrochalcones in Golden Delicious apples. Journal of Experimental Botany, 63(3), pp.1123-1133.
六、招生专业
生物育种、生物技术与工程等